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Piperine improves the sensitivity of osteosarcoma cells to doxorubicin by inducing apoptosis and inhibiting the PI3K/AKT/GSK-3β pathway

Abstract Background Osteosarcoma is a primary bone malignancy associated with the highest incidence rate. Chemotherapy for osteosarcoma has not substantially changed, and survival of patients with metastatic tumours has reached a plateau. Doxorubicin (DOX) is a broad-spectrum anti-osteosarcoma drug;...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yubin Qi, Lin Yao, Jianke Liu, Wen Wang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2023-03-01
Saila:Journal of Orthopaedic Surgery and Research
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s13018-023-03642-7
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