Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages

Abstract Background Axonal regeneration following peripheral nerve injury (PNI) depends on the complex interaction between Schwann cells (SCs) and macrophages, but the mechanisms underlying macrophage recruitment and activation in axonal regeneration remain unclear. Methods RNA sequencing (RNA-seq)...

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Autors principals:	Gang Yin, Yaofa Lin, Peilin Wang, Jun Zhou, Haodong Lin
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-06-01
Col·lecció:	Molecular Medicine
Matèries:	Schwann cells Macrophages Exosomes LncARAT Peripheral nerve repair
Accés en línia:	https://doi.org/10.1186/s10020-022-00501-9
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