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Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2

Summary: Vascular calcification (VC) is recognized as a crucial risk factor for cardiovascular diseases. Our previous report revealed that the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) plays a role in this process. However, the underlying molecular mechanisms remain elu...

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Principais autores: Yue Li, Wei Jie, Yanli Qi, Mingxing Mo, Yaxin Lian, Li Yin, Hui Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-02-01
coleção:iScience
Assuntos:
Nephrology
Biochemistry
Physiology
Molecular biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004223028432
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