Placenta-derived trophoblast extracellular vesicles promote CD169+ macrophage migration and suppress ovarian tumour growth

Abstract Background A lower survival rate due to a later stage of diagnosis requires a more effective therapy for ovarian cancer. Extracellular vesicles (EVs) have shown therapeutic potential in various diseases, partly due to their ability to modulate immune responses. We previously showed that pla...

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Detalhes bibliográficos

Principais autores:	Xinyi Sun, Lawrence W. Chamley, Terry Morgan, Sofian Tijono, Bridget Tsai, Leana Terblanche, Lai-Ming Ching, Qi Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
coleção:	Journal of Translational Medicine
Assuntos:	Extracellular vesicle Placenta Ovarian cancer CD169 Tumour xenograft model
Acesso em linha:	https://doi.org/10.1186/s12967-025-07320-6
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