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Efficacy and safety of inclisiran in patients with cerebrovascular disease: ORION-9, ORION-10, and ORION-11

Patients with cerebrovascular disease (CeVD) have been shown to benefit from lipid-lowering therapies, but guideline-recommended levels of low-density lipoprotein cholesterol (LDL-C) are often not attained with statin treatment alone. The ORION-9, ORION-10, and ORION-11 trials evaluated the efficacy...

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Principais autores: Wolfgang Koenig, Kausik K. Ray, Ulf Landmesser, Lawrence A. Leiter, Gregory G. Schwartz, R. Scott Wright, Lorena Garcia Conde, Jackie Han, Frederick J. Raal
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-06-01
Serier:American Journal of Preventive Cardiology
Fag:
Inclisiran
siRNA
Cerebrovascular disease
LDL-cholesterol
Safety
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666667723000442
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