Functional analysis of JPH2-knockout cardiomyocytes identifies ECCD as a novel indicator in a human cardiac modelJPH2

Abstract Background Junctophilin-2 (JPH2) is a vital protein in cardiomyocytes, anchoring T-tubule and sarcoplasmic reticulum membranes to facilitate excitation-contraction coupling, a process essential for cardiac contractile function. Dysfunction of JPH2 is associated with cardiac disorders such a...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Tianwei Guo, Hongyue Wang, Fujian Wu, Wenjing Lu, Min Zhu, Shuhong Ma, Yongshuai Zhang, Yuting Yan, Meng Zhou, Didaer Talanaite, Siyu Liu, Man Qi, Feng Lan, Xujie Liu
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-05-01
סדרה:	Stem Cell Research & Therapy
נושאים:	Junctophilin 2 Excitation-contraction coupling Cardiomyopathy Human embryonic stem cell-derived cardiomyocytes
גישה מקוונת:	https://doi.org/10.1186/s13287-025-04323-4
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!