Microbial genotoxin-elicited host DNA mutations related to mitochondrial dysfunction, a momentous contributor for colorectal carcinogenesis

ABSTRACT Gut microbe dysbiosis increases repetitive inflammatory responses, leading to an increase in the incidence of colorectal cancer. Recent studies have revealed that specific microbial species directly instigate mutations in the host nucleus DNA, thereby accelerating the progression of colorec...

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Hlavní autoři:	Xue Yang, Yumeng Gan, Yuting Zhang, Zhongjian Liu, Jiawei Geng, Wenxue Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2024-09-01
Edice:	mSystems
Témata:	colorectal cancer gut microbes genotoxins DNA mutation
On-line přístup:	https://journals.asm.org/doi/10.1128/msystems.00887-24
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