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Alternative splicing modulation by G-quadruplexes

Here the authors shows that G-quadruplexes, non-canonical DNA/RNA structures, can have a direct impact on alternative splicing and that binding of splicing regulators is affected by their presence.

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Principais autores: Ilias Georgakopoulos-Soares, Guillermo E. Parada, Hei Yuen Wong, Ragini Medhi, Giulia Furlan, Roberto Munita, Eric A. Miska, Chun Kit Kwok, Martin Hemberg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2022-05-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-022-30071-7
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