An accessible 3D HepG2/C3A liver spheroid model supporting the complete intrahepatocytic lifecycle of Plasmodium falciparum

Current liver-stage Plasmodium falciparum models are complex, expensive and largely inaccessible, hindering research progress. Here, we show that a 3D liver spheroid model grown from immortalized HepG2/C3A cells supports the complete intrahepatocytic lifecycle of P. falciparum. Our results demonstra...

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Autors principals:	Claire H. Caygill, Salwa Omar Alqurashi, Adriana Adolfi, Jessica Carson, Angelika Sturm, Daniel S. Evans, Jess B. Jinks, Koen J. Dechering, Lisa Reimer, Shaun H. Pennington, Parveen Sharma, Stephen A. Ward, Giancarlo A. Biagini
Format:	Artigo
Idioma:	Inglês
Publicat:	Cambridge University Press
Col·lecció:	Parasitology
Matèries:	HepG2/C3A malaria Plasmodium spheroids
Accés en línia:	https://www.cambridge.org/core/product/identifier/S0031182025100322/type/journal_article
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