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Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

In this manuscript the authors show that Filopodia switch between bundles of fascin-crosslinked actin and cofilin-decorated filaments, which exclude fascin binding due to altered structure and packing, as well as affect filopodial searching dynamics.

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Auteurs principaux: Ryan K. Hylton, Jessica E. Heebner, Michael A. Grillo, Matthew T. Swulius
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2022-05-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-022-30116-x
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