Efficacy of Adjuvant 5-Fluorouracil Therapy for Patients with EMAST-Positive Stage II/III Colorectal Cancer.

Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) is a genetic signature found in up to 60% of colorectal cancers (CRCs) that is caused by somatic dysfunction of the DNA mismatch repair (MMR) protein hMSH3. We have previously shown in vitro that recognition of 5-fluorou...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yasushi Hamaya, Carla Guarinos, Stephanie S Tseng-Rogenski, Moriya Iwaizumi, Ritabrata Das, Rodrigo Jover, Antoni Castells, Xavier Llor, Montserrat Andreu, John M Carethers
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2015-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC4440728?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!