Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops
Abstract Current computational methods on Hi-C analysis focused on identifying Mb-size domains often failed to unveil the underlying functional and mechanistic relationship of chromatin structure and gene regulation. We developed a novel computational method HiSIF to identify genome-wide interacting...
שמור ב:
| Principais autores: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2020-08-01
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| סדרה: | Genome Medicine |
| גישה מקוונת: | http://link.springer.com/article/10.1186/s13073-020-00769-8 |
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