Continuous adaptive chemotherapy dosing by using planet-formation-inspired dynamics: analytical and in silico insights

BackgroundCurrent therapeutic planning of chemotherapy is based on empirical dosimetry and intermittent dose administration, which can cause poorly defined therapeutic timepoints due to tumor heterogeneities and related highly uncertain tumor dynamics. Dynamic control strategies have been investigat...

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Hlavní autoři:	Marco P. Soares dos Santos, Sérgio X. F. Santos, Rodrigo M. C. Bernardo, João V. Vidal, Gil Gonçalves
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Oncology
Témata:	cancer treatment chemotherapy control continuous chemotherapy dosing dynamic control intermittent chemotherapy dosing planet formation
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1761791/full
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