Inverted H1 hemagglutinin nanoparticle vaccines protect mice against challenges with human H1N1 and bovine H5N1 influenza viruses

Abstract Influenza is a global health concern, causing over 300,000 deaths worldwide annually. Current vaccines and natural infection mainly elicit antibodies against the variable head domain of the hemagglutinin (HA) glycoprotein. While these antibodies are highly neutralizing, the head domain cons...

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Bibliografische Detailangaben

Hauptverfasser:	Asim Biswas, Kathryn Loeffler, Donguk Kim, Amie J. Eisfeld, Augustine Duffy, Hunter Hammond, Anjali Sangappa, Hassanein H. Abozeid, Gabriele Neumann, Alberto Moreno, Yoshihiro Kawaoka, Ravi S. Kane
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-11-01
Schriftenreihe:	npj Vaccines
Online-Zugang:	https://doi.org/10.1038/s41541-025-01276-w
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