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A Squaramide-Based Organocatalyst as a Novel Versatile Chiral Solvating Agent for Carboxylic Acids

A squaramide-based organocatalyst for asymmetric Michael reactions has been tested as a chiral solvating agent (CSA) for 26 carboxylic acids and camphorsulfonic acid, encompassing amino acid derivatives, mandelic acid, as well as some of its analogs, propionic acids like profens (ketoprofen and ibup...

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Principais autores: Fabio Spiaggia, Gloria Uccello Barretta, Anna Iuliano, Carlo Baldassari, Federica Aiello, Federica Balzano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-05-01
coleção:Molecules
Assuntos:
squaramide
chiral analysis
chiral auxiliary
NMR
enantiodiscrimination
diffusion coefficient
Acesso em linha:https://www.mdpi.com/1420-3049/29/10/2389
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