18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes

Abstract Background The tau positron emission tomography (PET) ligand 18F-flortaucipir binds to paired helical filaments of tau in aging and Alzheimer’s disease (AD), but its utility in detecting tau aggregates in frontotemporal dementia (FTD) is uncertain. Methods We performed 18F-flortaucipir imag...

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Κύριοι συγγραφείς:	Richard M. Tsai, Alexandre Bejanin, Orit Lesman-Segev, Renaud LaJoie, Adrienne Visani, Viktoriya Bourakova, James P. O’Neil, Mustafa Janabi, Suzanne Baker, Suzee E. Lee, David C. Perry, Lynn Bajorek, Anna Karydas, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Eliana M. Ramos, Giovanni Coppola, Maria Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William Jagust, Adam L. Boxer, Gil D. Rabinovici
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2019-01-01
Σειρά:	Alzheimer’s Research & Therapy
Θέματα:	Biomarkers Frontotemporal dementia Tau imaging Neuropathology Tau
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s13195-019-0470-7
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