Conservation and Divergence in the <italic toggle="yes">Candida</italic> Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control

ABSTRACT Candida biofilms resist the effects of available antifungal therapies. Prior studies with Candida albicans biofilms show that an extracellular matrix mannan-glucan complex (MGCx) contributes to antifungal sequestration, leading to drug resistance. Here we implement biochemical, pharmacologi...

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Detalhes bibliográficos

Principais autores:	Eddie Dominguez, Robert Zarnowski, Hiram Sanchez, Antonio S. Covelli, William M. Westler, Parastoo Azadi, Jeniel Nett, Aaron P. Mitchell, David R. Andes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2018-05-01
coleção:	mBio
Assuntos:	biofilm Candida non-albicans antifungal resistance extracellular matrix
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.00451-18
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