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Positive-unlabeled learning identifies vaccine candidate antigens in the malaria parasite Plasmodium falciparum

Abstract Malaria vaccine development is hampered by extensive antigenic variation and complex life stages of Plasmodium species. Vaccine development has focused on a small number of antigens, many of which were identified without utilizing systematic genome-level approaches. In this study, we implem...

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Hlavní autoři: Renee Ti Chou, Amed Ouattara, Matthew Adams, Andrea A. Berry, Shannon Takala-Harrison, Michael P. Cummings
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-04-01
Edice:npj Systems Biology and Applications
On-line přístup:https://doi.org/10.1038/s41540-024-00365-1
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