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Effects of histone acetyltransferase and deacetylase inhibitors on the expression of S100A genes after TLR4 and TLR2 stimulation in human dental pulp cells

Objectives: Histone acetylation has been suggested as a promising target for pharmacological intervention in regenerative endodontic (RET) and vital pulp therapy (VPT). S100 proteins are closely linked to processes affected by inhibitors of histone acetylation (HATi) and deacetylation (HDACi) (e.g....

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Hlavní autoři: Holger Jungbluth, Dominik Kraus, Diana Lalaouni, Sarah Hossam Fahmy, Jochen Winter, Søren Jepsen
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-07-01
Edice:Heliyon
Témata:
Histone acetylation
S100 proteins
S100A10
Gene expression
TLR2
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2405844025019024
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