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Pediatric acute lymphoblastic leukemia relapse and prognosis: key predictors and therapeutic implications

BackgroundPediatric acute lymphoblastic leukemia (ALL), the most common childhood malignancy, achieves >95% 5-year survival with risk-adapted therapies. Nonetheless, 10%–15% of patients experience relapse, with post-relapse survival <50%. Challenges remain in optimizing minimal residual diseas...

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Bibliographic Details
Main Authors: XiaoYan Chen, LingLing Wu, CaiYun Kuang, JiaYi Wang, WenGe Hao, Hua Jiang, WeiNa Zhang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2025-12-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1710578/full
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