Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway

Abstract Background Baicalin, which is isolated from Radix Scutellariae, possesses strong biological activities including an anti-inflammation property. Recent studies have shown that the anti-inflammatory effect of baicalin is linked to toll-like receptor 4 (TLR4), which participates in pathologica...

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Autori principali:	Li-Ting Guo, Si-Qi Wang, Jing Su, Li-Xing Xu, Zhou-Ye Ji, Ru-Yi Zhang, Qin-Wen Zhao, Zhan-Qiang Ma, Xue-Yang Deng, Shi-Ping Ma
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2019-05-01
Serie:	Journal of Neuroinflammation
Soggetti:	Depression Baicalin Neuroinflammation TLR4 FoxO1
Accesso online:	http://link.springer.com/article/10.1186/s12974-019-1474-8
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