Combination of Proteasomal Inhibitors Lactacystin and MG132 Induced Synergistic Apoptosis in Prostate Cancer Cells

The proteasome inhibitor Velcade (bortezomib/PS-341) has been shown to block the targeted proteolytic degradation of short-lived proteins that are involved in cell maintenance, growth, division, and death, advocating the use of proteasomal inhibitors as therapeutic agents. Although many studies focu...

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Hlavní autoři:	Robert B. Shirley, Ismail Kaddour-Djebbar, Dimpu M. Patel, Vijayabaskar Lakshmikanthan, Ronald W. Lewis, M. Vijay Kumar
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2005-12-01
Edice:	Neoplasia: An International Journal for Oncology Research
Témata:	Prostate apoptosis proteasomal inhibitors Lactacystin MG132
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1476558605800478
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