Platelet-rich plasma enhances local homing of umbilical cord-derived mesenchymal stem cells to articular cartilage by increasing the quantity and activation of integrin ꞵ1

Abstract Background Enhancing mesenchymal stem cells (MSCs) engraftment at the degenerative cartilage is important to increase the therapeutic effect of cartilage regeneration. Platelet-rich plasma (PRP) is known to have anti-inflammatory and anabolic effects for the treatment of osteoarthritis and...

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Autores principales:	Min Ji Lee, Soo Hyun Kim, Sue Shin, Tae Woo Kim, Chris Hyunchul Jo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-09-01
Colección:	Stem Cell Research & Therapy
Materias:	Cartilage regeneration Mesenchymal stem cells Homing Engraftment
Acceso en línea:	https://doi.org/10.1186/s13287-025-04593-y
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