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Ceramides and sphingomyelinases in senile plaques

The senile plaque is a hallmark lesion of Alzheimer disease (AD). We compared, without a priori, the lipidome of the senile plaques and of the adjacent plaque-free neuropil. The analysis by liquid chromatography coupled with electrospray ionization mass spectrometry revealed that laser microdissecte...

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Huvudupphov: Maï Panchal, Mathieu Gaudin, Adina N. Lazar, Elisa Salvati, Isabelle Rivals, Sophie Ayciriex, Luce Dauphinot, Delphine Dargère, Nicolas Auzeil, Massimo Masserini, Olivier Laprévote, Charles Duyckaerts
Materialtyp: Artigo
Språk:Inglês
Utgiven: Elsevier 2014-05-01
Serie:Neurobiology of Disease
Ämnen:
Alzheimer disease
Senile plaques
Laser microdissection
Lipidomics
Mass spectrometry
Ceramides
Länkar:http://www.sciencedirect.com/science/article/pii/S0969996114000242
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