Dexamethasone resets stable association of nuclear Snail with LSD1 concomitant with transition from EMT to partial EMT

Cancer cells utilize epithelial to mesenchymal transition (EMT) during invasion and metastasis. This program has intermediate cell states with retained epithelial and gained mesenchymal features together, referred to as partial EMT. Histone demethylase LSD1 forms a complex with the EMT master transc...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Satoshi Okuda, Nao Yamakado, Koichiro Higashikawa, Ryo Uetsuki, Fumi Ishida, Andra Rizqiawan, Shigehiro Ono, Kuniko Mizuta, Nobuyuki Kamata, Kei Tobiume
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-07-01
Schriftenreihe:	Biochemistry and Biophysics Reports
Schlagworte:	Epithelial to mesenchymal transition (EMT) Partial EMT Snail LSD1
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405580822000772
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