Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.

Influenza viruses (IV) cause pneumonia in humans with progression to lung failure and fatal outcome. Dysregulated release of cytokines including type I interferons (IFNs) has been attributed a crucial role in immune-mediated pulmonary injury during severe IV infection. Using ex vivo and in vivo IV i...

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Auteurs principaux:	Katrin Högner, Thorsten Wolff, Stephan Pleschka, Stephanie Plog, Achim D Gruber, Ulrich Kalinke, Hans-Dieter Walmrath, Johannes Bodner, Stefan Gattenlöhner, Peter Lewe-Schlosser, Mikhail Matrosovich, Werner Seeger, Juergen Lohmeyer, Susanne Herold
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2013-02-01
Collection:	PLoS Pathogens
Accès en ligne:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23468627/pdf/?tool=EBI
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