Further Characterization of the Capsule-Like Complex (CLC) Produced by Francisella tularensis Subspecies tularensis: Protective Efficacy and Similarity to Outer Membrane Vesicles

Francisella tularensis is the etiologic agent of tularemia, and subspecies tularensis (type A) is the most virulent subspecies. The live vaccine strain (LVS) of subspecies holarctica produces a capsule-like complex (CLC) that consists of a large variety of glycoproteins. Expression of the CLC is gre...

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Bibliografische Detailangaben

Hauptverfasser:	Anna E. Champion, Aloka B. Bandara, Nrusingh Mohapatra, Kelly M. Fulton, Susan M. Twine, Thomas J. Inzana
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2018-06-01
Schriftenreihe:	Frontiers in Cellular and Infection Microbiology
Schlagworte:	Francisella tularensis virulence factors capsule-like complex outer membrane vesicles protection immune response
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fcimb.2018.00182/full
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