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Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus

Abstract Plasmodium falciparum is the causative agent of malaria and remains a pathogen of global importance. Asexual blood stage replication, via a process called schizogony, is an important target for the development of new antimalarials. Here we use ultrastructure-expansion microscopy to probe th...

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Xehetasun bibliografikoak
Egile Nagusiak: Jiahong Li, Gerald J. Shami, Benjamin Liffner, Ellie Cho, Filip Braet, Manoj T. Duraisingh, Sabrina Absalon, Matthew W. A. Dixon, Leann Tilley
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2024-07-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-024-50167-6
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