Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury

Axon injury in the peripheral nervous system (PNS) induces a regeneration-associated gene (RAG) response. Atf3 (activating transcription factor 3) is such a RAG and ATF3's transcriptional activity might induce ‘effector’ RAGs (e.g. small proline rich protein 1a (Sprr1a), Galanin (Gal), growth-associ...

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Autori principali:	Manuel Gey, Renate Wanner, Corinna Schilling, Maria T. Pedro, Daniela Sinske, Bernd Knöll
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2016-01-01
Serie:	Open Biology
Soggetti:	atf3 axon regeneration facial nerve neuropeptide rag
Accesso online:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160091
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