Clinical Experience with Use of the PI3Kdelta Inhibitor Leniolisib to Treat Immune Dysregulation in Patients with CVID and CVID-Like Disorders

ObjectiveApproximately half of common variable immunodeficiency (CVID) patients develop debilitating and life-threatening clinical manifestations of immune dysregulation, including lymphoproliferation, cytopenias, interstitial lung disease (ILD), nodular regenerative hyperplasia of the liver (NRH),...

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Autors principals:	Gulbu Uzel, Monica Lawrence, Blanca Urban Vargas, Lorenzo Lodi, Kevin Thorneloe, Rebecca Marsh, Jason Bradt, Anurag Relan, Romina Dieli Crimi, Kate Howe, Valentina Guarnieri, Silvia Ricci, Aditi Jogdand, Jocelyn Farmer
Format:	Artigo
Idioma:	Inglês
Publicat:	Rockefeller University Press 2026-05-01
Col·lecció:	Journal of Human Immunity
Accés en línia:	https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.41/281928/Clinical-Experience-with-Use-of-the-PI3Kdelta
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