The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life

Abstract Specialized ribosomes help determine which proteins are synthesized, however, the influence of age on ribosome heterogeneity and whether dysregulation of this process drives organismal aging is unknown. Here we examined the role of ribosomal RNA (rRNA) methylation in maintaining appropriate...

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Autori principali:	M. Hafiz Rothi, Gautam Chandra Sarkar, Joseph Al Haddad, Wayne Mitchell, Kejun Ying, Nancy Pohl, Roberto G. Sotomayor-Mena, Julia Natale, Scarlett Dellacona, Vadim N. Gladyshev, Eric Lieberman Greer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-07-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-025-62323-7
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