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RNA helicase DEAD-box-5 is involved in R-loop dynamics of preimplantation embryos

Objective R-loops are DNA:RNA triplex hybrids, and their metabolism is tightly regulated by transcriptional regulation, DNA damage response, and chromatin structure dynamics. R-loop homeostasis is dynamically regulated and closely associated with gene transcription in mouse zygotes. However, the fac...

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Principais autores: Hyeonji Lee, Dong Wook Han, Seonho Yoo, Ohbeom Kwon, Hyeonwoo La, Chanhyeok Park, Heeji Lee, Kiye Kang, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Asian-Australasian Association of Animal Production Societies 2024-06-01
coleção:Animal Bioscience
Assuntos:
dead-box-5 (ddx5)
gene transcription
r-loop
zygote
Acesso em linha:http://www.animbiosci.org/upload/pdf/ab-23-0401.pdf
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