Synthesis and Evaluation of Novel ⁶⁸Ga-Labeled [D-Phe⁶,Leu¹³ψThz¹⁴]bombesin(6-14) Analogs for Cancer Imaging with Positron Emission Tomography

Gastrin-releasing peptide receptor (GRPR) is overexpressed in various cancers and is a promising target for cancer diagnosis and therapy. However, the high pancreas uptake and/or metabolic instability observed for most reported GRPR-targeted radioligands might limit their clinical applications. Our...

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Autori principali:	Lei Wang, Chao-Cheng Chen, Zhengxing Zhang, Hsiou-Ting Kuo, Chengcheng Zhang, Nadine Colpo, Helen Merkens, François Bénard, Kuo-Shyan Lin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-05-01
Serie:	Pharmaceuticals
Soggetti:	gastrin-releasing peptide receptor antagonist positron emission tomography Gallium-68 pancreas uptake
Accesso online:	https://www.mdpi.com/1424-8247/17/5/621
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