Characterization of isoniazid resistance and genetic mutations in isoniazid-resistant and rifampicin-susceptible Mycobacterium tuberculosis in China

Background: Patients with tuberculosis resistant to isoniazid but susceptible to rifampicin (Hr-Rs TB) remain a neglected demographic, despite a high disease burden and poor outcomes of these patients. The aim of this study was to investigate the characteristics of isoniazid-resistance-related mutat...

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Hlavní autoři:	Dongxin Liu, Bing Zhao, Yang Zheng, Xichao Ou, Shengfen Wang, Yang Zhou, Yuanyuan Song, Hui Xia, Qiang Wei, YanLin Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-09-01
Edice:	Infectious Medicine
Témata:	Mycobacterium tuberculosis Mono-isoniazid resistance Whole-genome sequencing Resistance mutation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2772431X24000431
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