Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

Abstract Background Angiostrongylus cantonensis is an important causative agent of eosinophilic meningitis and eosinophilic meningoencephalitis in humans. Previous studies have shown that the Sonic hedgehog (Shh) signaling pathway may reduce cell apoptosis by inhibiting oxidative stress in A. canton...

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Autori principali:	Kuang-Yao Chen, Lian-Chen Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-09-01
Serie:	Parasites & Vectors
Soggetti:	Angiostrongylus cantonensis Excretory/secretory products Astrocytes Sonic hedgehog signaling pathway NF-κB Cytokine
Accesso online:	http://link.springer.com/article/10.1186/s13071-017-2385-0
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