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Pseudomonas aeruginosa MipA-MipB envelope proteins act as new sensors of polymyxins

ABSTRACT Due to the rising incidence of antibiotic-resistant infections, the last-line antibiotics, polymyxins, have resurged in the clinics in parallel with new bacterial strategies of escape. The Gram-negative opportunistic pathogen Pseudomonas aeruginosa develops resistance to colistin/polymyxin...

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Principais autores: Manon Janet-Maitre, Viviana Job, Maxime Bour, Mylène Robert-Genthon, Sabine Brugière, Pauline Triponney, David Cobessi, Yohann Couté, Katy Jeannot, Ina Attrée
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2024-03-01
Series:mBio
Assuntos:
Pseudomonas aeruginosa
antibiotic resistance
polymyxin
ParR/ParS
arn
two-component system
Acceso en liña:https://journals.asm.org/doi/10.1128/mbio.02211-23
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