QR Code

Prevalence of alternative lengthening of telomeres in pediatric sarcomas determined by the telomeric DNA C-circle assay

IntroductionAlternative lengthening of telomeres (ALT) occurs in sarcomas and ALT cancers share common mechanisms of therapy resistance or sensitivity. Telomeric DNA C-circles are self-primed circular telomeric repeats detected with a PCR assay that provide a sensitive and specific biomarker exclusi...

Full description

Saved in:
Main Authors: Trevor A. Burrow, Balakrishna Koneru, Shawn J. Macha, Wenyue Sun, Frederic G. Barr, Timothy J. Triche, C. Patrick Reynolds
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Oncology
Subjects:
rhabdomyosarcoma
Ewing sarcoma
osteosarcoma
alternative lengthening of telomeres
telomere
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1399442/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items