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<italic toggle="yes">Mucor circinelloides</italic> Thrives inside the Phagosome through an Atf-Mediated Germination Pathway

ABSTRACT Mucormycosis is an emerging fungal infection that is often lethal due to the ineffectiveness of current therapies. Here, we have studied the first stage of this infection—the germination of Mucor circinelloides spores inside phagocytic cells—from an integrated transcriptomic and functional...

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Principais autores: Carlos Pérez-Arques, María Isabel Navarro-Mendoza, Laura Murcia, Carlos Lax, Pablo Martínez-García, Joseph Heitman, Francisco E. Nicolás, Victoriano Garre
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019-02-01
Serier:mBio
Fag:
emerging pathogens
host-pathogen interaction
innate immunity
mucormycosis
transcriptomics
Online adgang:https://journals.asm.org/doi/10.1128/mBio.02765-18
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