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Effect of Coenzyme-Q10 on Doxorubicin-Induced Nephrotoxicity in Rats

Nephrotoxicity is one of the limiting factors for using doxorubicin (Dox) as an anticancer chemotherapeutic. Here, we investigated possible protective effect of coenzyme-Q10 (CoQ10) on Dox-induced nephrotoxicity and the mechanisms involved. Two doses (10 and 100 mg/kg) of CoQ10 were administered ora...

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Autori principali: Azza A. K. El-Sheikh, Mohamed A. Morsy, Marwa M. Mahmoud, Rehab A. Rifaai, Aly M. Abdelrahman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2012-01-01
Serie:Advances in Pharmacological Sciences
Accesso online:http://dx.doi.org/10.1155/2012/981461
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