Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits

Abstract Background A lack of serotonin (also known as 5-hydroxytryptamine, 5-HT) in the brain due to deficiency of the rate-limiting enzyme in 5-HT synthesis, tryptophan hydroxylase 2 (TPH2), was recently reported to result in impaired maternal affiliation across species, including mice, rats, and...

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Autors principals:	Tianhua Wang, Judith R. Homberg, Laura Boreggio, Marta C. F. Samina, Rogério C. R. Castro, Sharon M. Kolk, Natalia Alenina, Michael Bader, Jinye Dai, Markus Wöhr
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-11-01
Col·lecció:	Molecular Autism
Matèries:	Serotonin Tryptophan hydroxylase 2 Autism Neurodevelopmental disorders Social behavior Ultrasonic vocalizations
Accés en línia:	https://doi.org/10.1186/s13229-024-00629-x
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