A multicenter, randomized, double-blind, placebo-controlled trial of amantadine to stimulate awakening in comatose patients resuscitated from cardiac arrest

Objective We hypothesized that the administration of amantadine would increase awakening of comatose patients resuscitated from cardiac arrest. Methods We performed a prospective, randomized, controlled pilot trial, randomizing subjects to amantadine 100 mg twice daily or placebo for up to 7 days. T...

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Detalhes bibliográficos

Principais autores:	Patrick J. Coppler, David J. Gagnon, Katharyn L. Flickinger, Jonathan Elmer, Clifton W. Callaway, Francis X. Guyette, Ankur Doshi, Alexis Steinberg, Cameron Dezfulian, Ari L. Moskowitz, Michael Donnino, Teresa L. May, David B. Seder, Jon C. Rittenberger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Korean Society of Emergency Medicine 2024-06-01
coleção:	Clinical and Experimental Emergency Medicine
Assuntos:	heart arrest coma brain hypoxia amantadine
Acesso em linha:	http://www.ceemjournal.org/upload/pdf/ceem-23-158.pdf
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