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Effects of pentoxifylline on whole blood IL‐2 and IFN‐gamma gene expression in normal dogs

Abstract Background Pentoxifylline (PTX) is a methylxanthine phosphodiesterase inhibitor that is used as a hemorrheologic and anti‐inflammatory agent in veterinary and human medicine. In human studies, PTX has been shown to decrease T‐cell production of cytokines such as IL‐2 and IFN‐γ. A RT‐qPCR as...

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Principais autores: Evangel Kummari, Andres Gibbs, Caitlin Riggs, Claire Fellman, John Stokes, John Thomason, Robert Wills, Andrew Mackin, Todd Archer
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2020-02-01
Series:Veterinary Medicine and Science
Assuntos:
cyclosporine
cytokine
dog
interferon‐γ
interleukin‐2
lymphocytes
Acceso en liña:https://doi.org/10.1002/vms3.204
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