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Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

Abstract Background The cholesterol gallstones diseases (CGD) is highly correlated with metabolic syndrome and type 2 diabetes. The present study aimed to investigate preventive effects of pioglitazone (PIO), an antidiabetic drug, on the CGD in guinea pigs fed with a lithogenic diet (LD). Methods Th...

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Principais autores: Tao Han, Yangge Lv, Shijia Wang, Tao Hu, Hao Hong, Zan Fu
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2019-12-01
סדרה:Lipids in Health and Disease
נושאים:
Pioglitazone
Gallstone
Lithogenic diet
Cholesterol
Bile acid
גישה מקוונת:https://doi.org/10.1186/s12944-019-1159-4
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