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MAD—microbial (origin of) Alzheimer’s disease hypothesis: from infection and the antimicrobial response to disruption of key copper-based systems

Microbes have been suspected to cause Alzheimer’s disease since at least 1908, but this has generally remained unpopular in comparison to the amyloid hypothesis and the dominance of Aβ and Tau. However, evidence has been accumulating to suggest that these earlier theories are but a manifestation of...

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Autori principali: Jin-Hong Min, Heela Sarlus, Robert A. Harris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-10-01
Serie:Frontiers in Neuroscience
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Accesso online:https://www.frontiersin.org/articles/10.3389/fnins.2024.1467333/full
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