Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells[S]

Sulfogalactosylglycerolipid (SGG) is the major sulfoglycolipid of male germ cells. During spermatogenesis, apoptosis occurs in >50% of total germ cells. Sertoli cells phagocytose these apoptotic germ cells and degrade their components using lysosomal enzymes. Here we demonstrated that SGG was a phys...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Hongbin Xu, Kessiri Kongmanas, Suraj Kadunganattil, Charles E. Smith, Tony Rupar, Naoko Goto-Inoue, Louis Hermo, Kym F. Faull, Nongnuj Tanphaichitr
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2011-12-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	spermatogenesis lysosomes electron microscopy
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520408235
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