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Mutations associated with a 17-gene leukemia stem cell score and the score’s prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia

Leukemia stem cells (LSC) are more resistant to standard chemotherapy and their persistence during remission can cause relapse, which is still one of the major clinical challenges in the treatment of acute myeloid leukemia (AML). A better understanding of the mutational patterns and the prognostic i...

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Главные авторы: Marius Bill, Deedra Nicolet, Jessica Kohlschmidt, Christopher J. Walker, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Xiaoqing Rong-Mullins, Zachary Brannan, Jonathan E. Kolitz, Bayard L. Powell, Kellie J. Archer, Adrienne M. Dorrance, Andrew J. Carroll, Richard M. Stone, John C. Byrd, Ramiro Garzon, Clara D. Bloomfield
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2020-03-01
Серии:Haematologica
Online-ссылка:https://haematologica.org/article/view/9290
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