Key features of the innate immune response is mediated by the immunoproteasome in microglia

Abstract Microglia are the resident immune cells of the central nervous system (CNS). We and others have shown that the inflammatory response of microglia is partially regulated by the immunoproteasome, an inducible form of the proteasome responsible for the generation of major histocompatibility co...

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Bibliografiska uppgifter

Huvudupphov:	Salman Izadjoo, Kasey E. Moritz, Guzal Khayrullina, Elizabeth M. Bergman, Brendan M. Melvin, Matthew W. Stinson, Summer G. Paulson, Nikki M. McCormack, Kelsey N. Anderson, Lunndon A. Lewis, Jeremy D. Rotty, Barrington G. Burnett
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Ämnen:	Immunoproteasome Microglia Innate immunity Complement Cytokines NFκ-B
Länkar:	https://doi.org/10.1038/s41598-025-25341-5
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