Ningxue Shengban decoction containing serum alleviates immune thrombocytopenia by modulating CD4+T cells balance via BMSCs-Exo-miR-199a-5p

Abstract Background The abnormal immune response mediated by CD4+T cells is a key factor in Immune thrombocytopenia(ITP) progression. While Ningxue Shengban Decoction (NXSBD) is an effective therapeutic, its underlying mechanism and targets remain obscure. Aim This study aims to clarify the role of...

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Autors principals:	Wuxia Yang, Yang Liu, Huiying Kang, Zhen Wang, Yanqi Song, Baoshan Liu, Aidi Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-02-01
Col·lecció:	Stem Cell Research & Therapy
Matèries:	Immune thrombocytopenia Treg miR199a-5p Bone marrow mesenchymal stem cells Exosomes
Accés en línia:	https://doi.org/10.1186/s13287-026-04936-3
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