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B Cell Tolerance in Health and Disease

B lymphocyte receptors are generated randomly during the bone marrow developmental phase of B cells. Hence, the B cell repertoire consists of both self and foreign antigen specificities necessitating specific tolerance mechanisms to eliminate self-reactive B cells. This review summarizes the major m...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Murali Gururajan, Vishal J. Sindhava, Subbarao Bondada
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2014-02-01
Schriftenreihe:Antibodies
Schlagworte:
Online-Zugang:http://www.mdpi.com/2073-4468/3/1/116
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