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Profiling of SARS-CoV-2 Subgenomic RNAs in Clinical Specimens

ABSTRACT SARS-CoV-2 transcribes a set of subgenomic RNAs (sgRNAs) essential for the translation of structural and accessory proteins to sustain its life cycle. We applied RNA-seq on 375 respiratory samples from individual COVID-19 patients and revealed that the majority of the sgRNAs were canonical...

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Autori principali: Zigui Chen, Rita Way Yin Ng, Grace Lui, Lowell Ling, Chit Chow, Apple Chung Man Yeung, Siaw Shi Boon, Maggie Haitian Wang, Kate Ching Ching Chan, Renee Wan Yi Chan, David Shu Cheong Hui, Paul Kay Sheung Chan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2022-04-01
Serie:Microbiology Spectrum
Soggetti:
RT-PCR
COVID-19
RNA-seq
SARS-CoV-2
subgenomic
Accesso online:https://journals.asm.org/doi/10.1128/spectrum.00182-22
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